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总结

研究团队在《自然》发表对人类脂质转运蛋白(LTPs)的系统性分析,梳理这些蛋白如何从膜或细胞内储库动员并转运不同脂质,建立细胞内“脂质运输地图”。结果揭示各类LTP在维持细胞膜完整性与脂质稳态中的分工与机制,为理解相关代谢异常、膜损伤与疾病发生提供线索,并为后续药物靶点筛选和细胞功能调控研究奠定基础。

正文

Systematic analyses of lipid mobilization by human lipid transfer proteins Nature Lipids have their own VIP drivers for reaching cellular targets Phys.org Researchers have created the first map of lipid transport in cells Universitetet i Bergen Researchers Uncover Mechanisms of Lipid Transfer Proteins in Regulating Cellular Membrane Integrity geneonline.com Unraveling Human Lipid Transfer Mechanisms Bioengineer.org
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