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总结

多家媒体报道,研究人员通过对不同年龄段女性卵子的细胞结构与代谢状态进行比较,获得了导致女性生育力随年龄下降的新线索:卵子在老化过程中可能出现能量供应受损、细胞器功能下降以及染色体分配更易出错等变化,从而降低受孕概率并提高胚胎异常与流产风险。研究团队还在体外条件下尝试对部分人类卵子进行“再活化/复原”处理,观察到部分质量指标改善,提示未来或可提高高龄女性试管婴儿成功率并为延长生育窗口的治疗提供方向,但相关技术仍处早期阶段,安全性、有效性与可推广性需更多临床验证。

正文

Scientists find new clues to why female fertility declines with age The Washington Post Human eggs 'rejuvenated' in an advance that could boost IVF success rates The Guardian Research into ageing eggs could pave way for fertility-extending treatments Caliber.Az IVF breakthrough for older women as eggs 'rejuvenated' The Independent Scientists say they have 'rejuvenated' human eggs in advance that could boost IVF success MadeForMums
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