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总结
一项汇总多项临床试验与随访研究的综述指出，许多使用GLP-1受体激动剂减重的人在停药后体重会反弹：平均约18个月开始明显回升，不到两年可能重新接近停药前水平；随之而来，血糖、血压等代谢指标的改善也可能减弱。报道强调，这类药物更接近长期慢病管理工具，若需停药应在医生指导下逐步调整，并与饮食、运动和行为干预结合，以降低复胖与健康风险回潮。
正文
Many people who come off GLP-1 drugs regain weight within 2 years, review suggests CNN Former GLP-1 users regain lost weight after about 18 months, study says The Washington Post People coming off weight-loss injections risk fast weight gain BBC Less than two years after stopping obesity drugs, weight and health issues return, study finds Reuters People who stop taking weight-loss jabs regain weight in under two years, study reveals The Guardian
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