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总结
多家媒体援引综述和研究指出，使用GLP‑1类减重注射药物的人一旦停药，体重反弹的“倒计时”随即开始。数据显示，不少人在停药后约18个月出现明显回升，两年内可能重新增加大部分减重，并伴随血糖、血压等代谢指标回到用药前水平。报道称，部分人因费用、供货、妊娠计划或不良反应而停用，这使临床更关注长期依从性、逐步减量与生活方式干预的结合，以降低反弹风险。
正文
The clock starts ticking the day you quit your GLP‑1 medication Scripps News People coming off weight-loss injections risk fast weight gain BBC Many people who come off GLP-1 drugs regain weight within 2 years, review suggests CNN Former GLP-1 users regain lost weight after about 18 months, study says The Washington Post Less than two years after stopping obesity drugs, weight and health issues return, study finds Reuters
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