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总结
多家媒体报道，一项阿尔茨海默病小鼠研究发现，雌性大脑的免疫反应强于雄性，提示性别可能影响神经炎症水平及疾病进程。研究聚焦免疫细胞在脑内的反应差异，指出在药物试验与疗效评估中需要更“富集”的患者数据与更细的性别分层，以识别男女在治疗反应上的差别并优化试验设计。该结果为个体化治疗与未来临床研究提供线索，但结论仍需在人群中进一步验证。
正文
Study in mice with Alzheimer's finds higher immune response in female brain than in male Press Trust of India Alzheimer's Immune Response Higher In Females' Brain Than In Males, Finds New Study NDTV Enriched patient data needed to uncover sex differences in Alzheimer's trials Pharmaceutical Technology Researchers Call for Enriched Patient Data to Address Sex Differences in Alzheimer's Treatment Effects geneonline.com Uncovering Gender Differences in Alzheimer's: The Role of Immune Cells Devdiscourse
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