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总结
多家媒体报道，研究人员在阿尔茨海默病相关研究中发现显著性别差异。基于小鼠模型的实验显示，雌性大脑的免疫反应强度高于雄性，提示免疫细胞活动可能在疾病发生与进展中扮演不同角色。与此同时，相关报道强调在阿尔茨海默病临床试验中需要更“富集”的患者数据与更细化的分层分析，以识别不同性别在治疗反应和疗效上的差异，从而为制定更精准的治疗策略、优化试验设计及理解免疫机制带来影响。
正文
Study in mice with Alzheimer's finds higher immune response in female brain than in male Daily Excelsior Alzheimer's Immune Response Higher In Females' Brain Than In Males, Finds New Study NDTV Enriched patient data needed to uncover sex differences in Alzheimer's trials Pharmaceutical Technology Researchers Call for Enriched Patient Data to Address Sex Differences in Alzheimer's Treatment Effects geneonline.com Uncovering Gender Differences in Alzheimer's: The Role of Immune Cells Devdiscourse
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